InhaltsangabePeripheral and Central Mechanisms of Pain Generation.- Drugs in Clinical Use.- Opioids.- Antipyretic Analgesics: Nonsteroidal Antiinflammatory Drugs, Selective COX-2 Inhibitors, Paracetamol and Pyrazolinones.- Local Anesthetics.- Serotonin Receptor Ligands: Treatments of Acute Migraine and Cluster Headache.- Anti-convulsants and Anti-depressants.- Compounds in Preclinical Development.- Neuropeptide and Kinin Antagonists.- Glutamate Receptor Ligands.- Adrenergic and Cholinergic Compounds.- Cannabinoids and Pain.- Future Targets in Analgesia Research.- Adenosine and ATP Receptors.- Ion Channels in Analgesia Research.- Protein Kinases as Potential Targets for the Treatment of Pathological Pain.- Pain Management Beyond Pharmacotherapy.- Placebo and Endogenous Mechanisms of Analgesia.- Limitations of Pharmacotherapy: Behavioral Approaches to Chronic Pain.