This book provides an overview of circadian rhythms and cellular networks in their relation to biological systems and dynamical medicine. Six concise chapters explore circadian cell rhythms and biomarkers in inflammation, cardiovascular disease, cancer, depression, and more in causing and treating these ailments. The final chapter discusses optimization of drug delivery and individualized treatment systems using chronotherapy and chronobiology-based biomarkers as a general system of medicine. Succinct yet comprehensive, Cellular Rhythms and Networks, part of SpringerBriefs in Cell Biology presents a novel framework for clinical applications in personalized and systems medicine. It is invaluable reading for researchers and clinicians in cell biology, mood disorders, and systems medicine.

Dr. Qing Yan received his Ph.D. in Biological and Medical Informatics from the University of California San Francisco (UCSF). He has extensive research experience in the biomedical sciences and leadership experience in the biopharmaceutical industry. His research interests include bioinformatics; systems biology; pharmacogenomics; immunology; neuroscience; personalized medicine; and translational medicine. Dr. Yan has published many research papers and edited four books on biomedical topics.

1.Introduction: Cellular Rhythms and Networks in Systems andDynamical Medicine

.-1 Introduction: Cellular Rhythms and Networks in Systems and Dynamical Medicine.-2Circadian Rhythms and Cellular Networks: A Systems Biology Perspective.-3 The Circadian-Immune Crosstalk and Inflammation: Implications for Disease Treatment.-4 Circadian Rhythms and Cellular Networks in Depression and Associated Disorders .-5Circadian Rhythms and Cellular Networks in Cardiovascular Diseases.-6Circadian Rhythms and Cellular Networks in Cancer.-7Circadian Biomarkers and Chronotherapy: Implications for Personalized and Systems Medicine