Essential resource for the fight against emerging infectious diseases

Incidences such as the 2014 Ebola epidemic in West Africa and the 2015 appearance of Zika in Brazil provide dramatic evidence of the continued ability of microbes to emerge, spread, adapt, and threaten global health. The challenge facing infectious disease specialists and public health professionals is to improve and find new diagnostic, therapeutic, and prevention strategies.

The editors of the 10th installment of the Emerging Infections series have compiled the perspectives of leading infectious disease experts into 22 chapters that provide important updates on a broad range of emerging and reemerging bacterial, viral, parasitic, and fungal infectious diseases in the United States and globally. In addition to focusing on MERS, Ebola virus disease, chikungunya, and Zika virus disease,Emerging Infections 10 explores the global threat of antimicrobial resistance in reviews on carbapenem-resistant Enterobacteriaceae, multiply-resistant gonococcal infections, non-typhoidal Salmonella infections, and artemisinin-resistant Plasmodium falciparum malaria. Topics include both recently- and long-recognized diseases that pose challenges for the clinical, laboratory, research, public health, and animal health communities.

Emerging Infections 10 presents new and emerging strategies to prevent, control, and eradicate infectious diseases and guides readers to the primary literature where they can explore individual topics in greater depth. This book is a valuable reference for professionals in microbiology, epidemiology, public health, and clinical and veterinary medicine.

Contributors ix

Foreword xv

Preface xvii

Acknowledgments xix

1 West Africa 2013: Re-examining Ebola 1Daniel G. Bausch and Amanda Rojek

2 Preparing for Serious Communicable Diseases in the United States: What the Ebola Virus Epidemic Has Taught Us 39Jay B. Varkey and Bruce S. Ribner

3 Ebola Virus Disease: Therapeutic and Potential Preventative Opportunities 53Robert Fisher and Luciana Borio

4 Middle East Respiratory Syndrome (MERS) 73Sonja A. Rasmussen, Amelia K. Watson, and David L. Swerdlow

5 The Emergence of Enterovirus D-68 105Kevin Messacar, Mark J. Abzug, and Samuel R. Dominguez

6 The Role of Punctuated Evolution in the Pathogenicity of Influenza Viruses 121Jonathan A. McCullers

7 Measles in the United States since the Millennium: Perils and Progress in the Postelimination Era 131Anne Schuchat, Amy Parker Fiebelkorn, and William Bellini

8 Chikungunya Virus: Current Perspectives on a Reemerging Virus 143Clayton R. Morrison, Kenneth S. Plante, and Mark T. Heise

9 Zika Virus Disease 163Werner Slenczka

10 West Nile Virus Infection 175James J. Sejvar

11 Mobilization of Carbapenemase-Mediated Resistance in Enterobacteriaceae 201Amy Mathers

12 Antimicrobial Resistance Expressed by Neisseria gonorrhoeae: A Major Global Public Health Problem in the 21st Century 213Magnus Unemo, Carlos del Rio, and William M. Shafer

13 Bordetella holmesii: Still Emerging and Elusive 20 Years On 239Laure F. Pittet and Klara M. Posfay-Barbe

14 Cronobacter spp. 255Brian P. Blackwood and Catherine J. Hunter

15 Clostridium difficile Infection 265Jae Hyun Shin, Esteban Chaves-Olarte, and Cirle A. Warren

16 Emerging Tick-Borne Bacterial Pathogens 295Tahar Kernif, Hamza Leulmi, Didier Raoult, and Philippe Parola

17 Bordetella pertussis 311Delma J. Nieves and Ulrich Heininger

18 Invasive Infections with Nontyphoidal Salmonella in Sub-Saharan Africa 341Barbara E. Mahon and Patricia I. Fields

19 Fungal Infections Associated with Contaminated Steroid Injections 359Carol A. Kauffman and Anurag N. Malani

20 Emerging Fungal Infections in the Pacific Northwest: The Unrecognized Burden and Geographic Range of Cryptococcus gattii and Coccidioides immitis 375Shawn R. Lockhart, Orion Z. McCotter, and Tom M. Chiller

21 The Emerging Amphibian Fungal Disease, Chytridiomycosis: A Key Example of the Global Phenomenon of Wildlife Emerging Infectious Diseases 385Jonathan E. Kolby and Peter Daszak

22 Artemisinin-Resistant Plasmodium falciparum Malaria 409Rick M. Fairhurst and Arjen M. Dondorp

Index 431