This revised and expanded edition highlights the importance of understanding the biologic and psychologic pain mechanisms to prepare clinicians who treat patients presenting with a variety of pain symptoms. The authors include evidence-based research on how the pain experience may be influenced by genetics, gender, or individual psychosocial and health histories. Extending well beyond basic toothache and TMDs, this book covers pathologic conditions of surrounding orofacial structures and nonodontogenic pain disorders that may manifest as orofacial pain as well. Chapters on management guide clinicians on how to develop practical and compassionate treatment plans based on logical evaluation methods, accurate diagnosis, and appropriate pharmacologic treatment, or how to decide when referral to other health care providers is warranted. A series of case studies demonstrates the effective application of this information to clinical situations.

"1. What is Pain and How Do We Classify Orofacial Pain?2. Epidemiology of Orofacial Pain: Prevalence, Incidence, and Risk Factors3. Current Beliefs and Educational Guidelines4. Peripheral Mechanisms of Orofacial Pain5. Central Nociceptive Pathways6. Neurochemical Factors in Injury and Inflammation of Orofacial Tissues7. Mechanisms of Neuropathic Pain8. Pain Modulatory Systems9. Pain and Genetics10. Measurement of Pain11. Psychologic State and Pain Perception12. Psychosocial Issues13. Pain and Gender14. Pain and Motor Reflexes15. Persistent Pain and Motor Dysfunction16. Pain and Sleep Disturbances17. The Path to Diagnosis18. Evidence-Based Pain Management19. Management of Persistent Orofacial Pain20. Management of Dental Pain21. Management of Inflammatory Pain22. Management of Masticatory Myalgia and Arthralgia23. Management of Mucosal Pain24. Management of Neuropathic Pain25. Management of Orofacial Pain Related to Headache: Principles and Practice26. Management of Movement Disorders Related to Orofacial Pain: Principles and Practice27. Illustrative Case Reports28. Science Transfer in Orofacial Pain: Problems and Solutions"