In this text, a theory for general linear parabolic partial differential equations is established which covers equations with inhomogeneous symbol structure as well as mixed-order systems. Typical applications include several variants of the Stokes system and free boundary value problems. We show well-posedness inLp-Lq-Sobolev spaces in time and space for the linear problems (i.e., maximal regularity) which is the key step for the treatment of nonlinear problems. The theory is based on the concept of the Newton polygon and can cover equations which are not accessible by standard methods as, e.g., semigroup theory. Results are obtained in different types of non-integerLp-Sobolev spaces as Besov spaces, Bessel potential spaces, and TriebelLizorkin spaces. The last-mentioned class appears in a natural way as traces ofLp-Lq-Sobolev spaces. We also present a selection of applications in the whole space and on half-spaces. Among others, we prove well-posedness of the linearizations of the generalized thermoelastic plate equation, the two-phase NavierStokes equations with BoussinesqScriven surface, and theLp-Lq two-phase Stefan problem with GibbsThomson correction.

Introduction and Outline.- 1 The joint time-space H(infinity)-calculus.- 2 The Newton polygon approach for mixed-order systems.-3 Triebel-Lizorkin spaces and the Lp-Lq setting.- 4 Application to parabolic differential equations.- List of figures.-Bibliography.- List of symbols.- Index.