Marine organisms are a wonderful source of biologically active natural products. Sea cucumbers are among the marine organisms which use as traditional food, especially in Asia. They are cylinder-shaped invertebrates that live in a variety of sea floor habitats from warm tropical waters to cold deep-sea trenches. Holothuria atra is the most important and abundant sea cucumber species in the Red Sea on the Saudi Arabia coast. Sea cucumber contains physiologically active phenolic compounds with antioxidant activity, which afforded a potential therapeutic activity against hepatorenal diseases.

Dr. Ayman Saber Mohamed was born in Giza, Egypt, 1984. He graduated from Cairo university in 2011 and received his M.Sc degrees in molecular and integrated physiology from the Department of Zoology, Faculty of Science, Cairo University in 2014.