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Extraction of Pure Ketamine Powder and Study their Analgesic Effect as a Gel on

Akademische Schriftenreihe V209705

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Erschienen am 01.03.2013, Auflage: 1. Auflage
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Bibliografische Daten
ISBN/EAN: 9783656382805
Sprache: Englisch
Umfang: 32

Beschreibung

Scientific Essay from the year 2012 in the subject Chemistry - Other, grade: 3, University of Mosul, course: Dental Chemistry, language: English, abstract: The present study was undertaken to extract ketamine powder from ketamine hydrochloride by precipitate ketamine. After that we examine the purity of this powder by infra-red (FTIR) and ultra-violet(UV) spectroscopy. ketamine gel in different concentrations was prepared ( 0.5, 1, 5, 10, 15 )% to evaluate the antinociceptive activity. ketamine powder was seen is pure and this show in infra-red and ultra-violet scanner. Ketamine gel at concentrations 0.5, 1, 5, 10,15) % produce antinociceptive in mice (5.6±2.2) (4.4±2.0) (8.2±4.3) (10.6±5.2) (8±2.1) second after 2 min respectively by using a hot plate test in comparison with control(2.4±2). The percentage of maximum possible effect (MPE) increased from (9.9) % in control group to (23.3) (18.3) (34.2) (44.2) (33.3)% respectively according to the concentrations of ketamine gel after 2 min. Purification of ketamine powder from ketamine solution and use as a gel to could be of value relief pain by topical application.

Autorenportrait

Name: AMER A. TAQA Email: amertaqa@hotmail.com DEPARTMENT OF DENTAL BASIC SCIENCE COLLEGE OF DENTISTRY/MOSUL UNIVERSITY/IRAQ EDUCATION PhD in Inorganic Chemistry awarded in 2001. Dissertation Title " Preparation and study some of complexes that can be used as dental restorative. Advisor: Tahanee Al-Sandook and I.M.Ahmed. M.Sc in inorganic Chemistry awarded in 1991. Dissertation Title" Preparation and study some of uranium complexes with nitrones" Advisor: Wiseman Aziz. B.Sc in Chemistry awarded in 1985. EXPERIENCE Professor teaching in Dental Basic Science Mosul University 1993to present. Head of Dept. of Dental Basic Sciences - 2003 to 2005 Registrar of Dept. of Dental Basic Sciences -1995 to 2003 Professor 2009 Assistant Professor - 1999 Lecturer 1995 Assistant lecturer 1993 Postgraduate MSc Supervision Student in an inorganic Chemistry in Science College. Seven students in Prosthetic in Dentistry College. One student in orthodontic in Dental College. Three students in Operative in Dental College.

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