The international conference \Operations Research 2008", the annual meeting of the German Operations Research Society (GOR), was held at the University of Augsburg on September 3-5, 2008. About 580 p- ticipants from more than 30 countries presented and listened to nearly 400 talks on a broad range of Operations Research. The general subject \Operations Research and Global Business" str- ses the important role of Operations Research in improving decisions in the increasingly complex business processes in a global environment. The plenary speakers Morris A. Cohen (Wharton School) and Bernd Liepert (Executive Board of KUKA Robotics) addressed this subject. Moreover, one of the founders of Operations Research, Saul Gass (U- versity of Maryland), gave the opening speech on the early history of Operations Research. This volume contains 93 papers presented at the conference, selected by the program committee and the section chairs, forming a representative sample of the various subjects dealt with at Operations Research 2008. The volume follows the structure of the conference, with 12 sections, grouped into six \Fields of Applications" and six \Fields of Methods and Theory". This structure in no way means a separation of theory and application, which would be detrimental in Operations Research, but displays the large spectrum of aspects in the focus of the papers. Of course, most papers present theory, methods and applications together.