Scientific Essay from the year 2005 in the subject Pharmacology, grade: Keine, , course: 1. Deutscher Kongress für Patientensicherheit bei medikamentöser Therapie, Congresshalle, Saarbrücken, Germany, language: English, abstract: Signal Validation can lead VigilanceJust single ADRs relating the known benzene toxicologic endpoints (leukemia, breast cancer) and these substances are worth to be investigated completely, since they enable risk assessments based on predisposition and epidemiology much earlier. The need of intelligence tools to deal with such heterogeneous data is obvious. The paradoxical situation that often arises is characterized by information overload but knowledge deficiency, and the need for intellectual involvement in information assimilation4. IT tools for intelligence are designed to assess risks in situations when only bits and pieces of knowledge are available but the situation forces to find the trace of future and past events (like it is the case in criminology, counter-terrorism, and military intelligence).