This book is a guide to pharmacotherapy treatment of tobacco dependence. The 2020 American Thoracic Society clinical practice guidelines on treating tobacco dependence serves as the cornerstone for this work with its robust discussion of recommended treatment options and how to tailor treatment to specific patient populations. Tobacco dependence remains a major health concern for many adults and given the dramatic increase of youth electronic cigarette use, clinicians need a singular resource to treat these different populations. This book addresses that by following the three main points of how to best address the adverse impact of tobacco use on public health: 1) prevent initiation of tobacco use; 2) understand mechanisms of addiction; 3) effectively treat tobacco dependence.The book begins by describing the current patterns of product use, the adverse impact of tobacco on global health, and tobacco-related health disparities. Authors discuss both combustible andelectronic tobacco products, as well as current research on the adverse impact of vaping and associated flavorings including menthol, role of the e-cigarette in cessation, and treatment of adolescent nicotine dependence. Chapters conclude with a discussion of specific tobacco control policies to improve overall public health.  This is an ideal guide for pulmonologists, pediatricians, primary care physicians and other specialty providers who see patients with nicotine dependence. This book is also of interest to public health professions to help inform public health campaigns and treatment offerings to reduce overall tobacco product use through prevention and treatment.

Dr. Michelle Eakin is a health psychologist and an Associate Professor at Johns Hopkins University School of Medicine. Her research focuses on community based interventions to reduce tobacco exposure. She has been the PI and co-investigator on multiple NIH funded studies to evaluate the effectiveness of behavioural interventions to promote health behaviour change and reduce health disparities. She is the past chair of the Tobacco Action Committee for the American Thoracic Society.

Dr. Kathuria is a Pulmonary and Critical Care physician at Boston Medical Center and an Associate Professor at Boston University Medical School. She directs the Tobacco Treatment Center at Boston Medical Center. Her current research, advocacy, and clinical efforts are focused on clinical care and policy surrounding tobacco dependence in underserved populations. She serves as chair of the ATS Tobacco Action Committee and co-chair of the ATS Tobacco Task Force. She is the Section Editor to UpToDate,Tobacco Treatment.

Current Patterns of Tobacco Use and Health Disparities.- Adverse Effects of Tobacco Products (Cigarettes, E-Cigarettes, Hookah, Smokeless tobacco) Use on Health.- Neurobiology and Mechanisms of Nicotine Addiction.- Pharmacotherapy for the Treatment of Tobacco Dependence.- Non-Pharmacologic Approaches to Tobacco Cessation.- Tobacco Dependence and Marginalized Populations Key Considerations for Health Care Providers.- Treating Nicotine Dependence in the Pediatric Setting: Adolescents and Caregivers Who Smoke.- Treatment of Tobacco Dependence in the Inpatient Setting.- Integration of Tobacco Dependence Treatment in Lung Cancer Screening and Other Ambulatory Care Settings.- Bringing treatment to the patients: Community-based tobacco-dependence treatment and interventions.- E-Cigarette: Friend or Foe?.- Role of menthol and other flavors on tobacco and nicotine product use.- Promoting training and education in tobacco dependence treatment.- Increasing Access to Treatment for Nicotine Dependence.- Tobacco control policies to reduce tobacco use.