This book provides readers with an overview of recent theories and methods for studying complex mechanical systems used in energy production, such as wind turbines, but not limited to them. The emphasis is put on strategies for increasing energy efficiency, and on recent industrial applications. Topics cover dynamics and vibration, vibroacoustics, engineering design, modelling and simulation, fault diagnostics, signal processing and prognostics. The book is based on peer-review contributions and invited talks presented at the first International Workshop on MOdelling and Simulation of COmplex Systems for Sustainable Energy Efficiency, MOSCOSSEE 2021, held online on February 25-26, 2021, and organized by the LAboratory of Mechanics, Modelling and Production (LA2MP) from University of Sfax, Tunisia and the Department of Mechanical and Aeronautical engineering, Centre of Asset Integrity Management (C-AIM) from University of Pretoria, South Africa. By offering authoritative information on innovative methods and tools for application in renewable energy production, it provides a valuable resource to both academics and professionals, and a bridge to facilitate communication between the two groups.