This book is the first authoritative and comprehensive volume dedicated to epicardial adipose tissue (EAT). It provides an up-to-date and highly illustrated synopsis of the anatomical, biomolecular, genetic, imaging features, and clinical applications of EAT and its role in cardiovascular disease.

It relays to the reader a contemporary view of the emerging interplay between the heart and adiposity-related diseases. In addition, this volume discusses the clinical implications and therapeutic targets of EAT in atrial fibrillation, heart failure and coronary artery disease.

Comprehensive yet focused,Epicardial Adipose Tissue: From Cell to Clinic is an essential resource for physicians, residents, fellows, and medical students in cardiology, endocrinology, primary care, and health promotion and disease prevention.

Gianluca Iacobellis MD, PhD

Professor of Medicine

Division of Endocrinology, Diabetes and Metabolism

University of Miami, Miller School of Medicine

Miami, FL

1. Epicardial Adipose Tissue (EAT) Embriology.- 2. EAT in Animals.- 3. EAT Anatomy.- 4. EAT Bio-molecular Physiology and Pathophysiology.- 5. EAT Genetic Physiology and Pathophysiology.- 6. Transcriptome of Epicardial Fat.- 7. Interaction between Epicardial Fat and Aldosterone-Angiotensin system.- 8. Epicardial Fat Lipidomics.- 9. EAT Imaging (Echo, CTA, MRI) .- 10. EAT Clinical Implications.- 11. EAT Therapeutic Targets.- 12. Epicardial Fat and Atrial Fibrillation.- 13. Neuroendocrine Modulation of Epicardial Fat in Heart Failure and Atrial Fibrillation.- 14. Perivascular Fat and Atherosclerosis.- 15. EAT Randomized Controlled Trials.- 16. Future Directions.