Cases in Medical Microbiology and Infectious Diseases challenges students to develop a working knowledge of the variety of microorganisms that cause infections in humans. This valuable, interactive text will help them better understand the clinical importance of the basic science concepts presented in medical microbiology or infectious disease courses.

The cases are presented as "unknowns" and represent actual case presentations of patients the authors have encountered. Each case is accompanied by several questions to test knowledge in four broad areas including the organism's characteristics and laboratory diagnosis; pathogenesis and clinical characteristics of the infection; epidemiology; and prevention and, in some cases, drug resistance and treatment.

This newfourth edition includes:

an entirely new section, "Advanced Cases," which includes newly recognized disease agents as well as highly complex cases where the interaction of the immune system and human pathogens can be more closely examineda revised "Primer on the Laboratory Diagnosis of Infectious Diseases" section that reflects the increasing importance of molecular-based assaysForty-two new cases that explore the myriad advances in the study of infectious disease in the past decadeThirty-two updated cases that reflect the current state of the art as it relates to the organism causing the infection

This textbook also include specific tools to assist students in solving the cases, including a table of normal values, glossary of medical terms, and figures illustrating microscopic organism morphology, laboratory tests, and clinical symptoms.Cases in Medical Microbiology and Infectious Diseases is a proven resource for preparing for Part I of the National Board of Medical Examiners Exam and an excellent reference for infectious disease rotations.

Peter H. Gilligan, Ph.D, has been Associate Director and now Director of the Clinical Microbiology-Immunology Laboratories at the University of North Carolina Hospitals for the past 30 years. During that time he has been highly engaged in educating health care providers at all levels in clinical aspects of medical microbiology. An ABMM-board certified microbiologist, he received his Ph.D. in Microbiology from the University of Kansas followed by a Medical Microbiology and Public Health Fellowship at the University of North Carolina Hospitals. His research interests are in the laboratory diagnosis of emerging pathogens, particularly in agents of chronic lung infection in cystic fibrosis patients.

Daniel S. Shapiro, M.D., a board-certified infectious diseases specialist, spent 20 years as the director of clinical microbiology laboratories at hospitals in the Boston area (Lahey Clinic; Boston Medical Center and its predecessor institutions Boston City Hospital and Boston University Hospital) prior to becoming Chair of Internal Medicine at the University of Nevada School of Medicine in Reno. A graduate of M.I.T., following his internal medicine residency at Massachusetts General Hospital he completed fellowships in both infectious diseases and clinical microbiology at the University of North Carolina Hospitals, where he trained in Dr. Gilligans laboratory. His area of particular interest is zoonotic infections.

Melissa B. Miller, Ph.D., D(ABMM), is an Associate Professor of Pathology and Laboratory Medicine at the University of North Carolina at Chapel Hill School of Medicine. She is Director of the Molecular Microbiology Laboratory and Associate Director of the Microbiology-Immunology Laboratory for UNC Health Care. Dr. Miller received her Ph.D. in Molecular Biology from Princeton University and completed the Medical and Public Health Microbiology Fellowship at the UNC Hospitals. Her research focus is in microbial epidemiology and antimicrobial resistance and the development and assessment of molecular diagnostic assays for the detection of pathogens.

Table of Normal Values Inside Front Cover

Acknowledgments

Introduction to the Fourth Edition

To the Student

A Primer on the Laboratory Diagnosis of Infectious Diseases

One Urogenital Tract Infections

Two Respiratory Tract Infections

Three Gastrointestinal Infections

Four Skin and Soft Tissue Infections

Five Central Nervous System Infections

Six Systemic Infections

Seven Advanced Cases

Glossary

Index