Clinical Medicine Lecture Notes provides a comprehensive, accessible introduction to the management and treatment of medical conditions. A short manual of techniques on communication and physical examination in Part 1 is supported by the core knowledge required on diseases specific to each body system in Part 2.

Combining readability with high quality illustrations, this seventh edition has been thoroughly revised to reflect up to date practice in examination and clinical investigation, and advances in the evidence base supporting modern day clinical practice. Numerous figures and tables help distil the information for revision purposes, and there are new chapters on the medical interview and assessment.

Whether you need to develop your knowledge for clinical practice, or refresh that knowledge in the run up to examinations,Clinical Medicine Lecture Notes will help foster a systematic approach to the clinical situation for all medical students and hospital doctors.

John Bradley, Consultant Physician, Addenbrooke's Hospital and Cambridge Medical School, Cambridge, UK

Mark Gurnell, University Department of Medicine, Addenbrooke's Hospital, Cambridge, UK

Diana Wood, Director of Medical Education, School of Clinical Medicine, University of Cambridge, UK

David Rubenstein, Consultant Physician, Addenbrooke's Hospital, Cambridge, UK

David Wayne, Consultant Physician, James Paget Hospital, Great Yarmouth, UK

Preface to the Seventh Edition iv

Preface to the First Edition v

Part 1 Clinical Examination

1 The medical interview 1

2 General examination 7

3 Cardiovascular system 10

4 Respiratory system 19

5 The abdomen 28

6 Neurological system 39

7 Endocrinology and metabolism 57

8 Musculoskeletal system 62

9 Assessment 66

Part 2 Clinical Medicine

10 Cardiovascular disease 73

11 Respiratory disease 110

12 Gastroenterology 128

13 Liver disease 144

14 Renal disease 153

15 Neurology 171

16 Endocrine disorders 208

17 Metabolic disorders 229

18 Rheumatology 269

19 Dermatology 297

20 Haematology 321

21 Infectious diseases 336

22 Toxicology 351

SI Units conversion table 361

Index 362

The plate section can be found facing page 314